abstract：PURPOSE:To investigate the independent impact of the incidence and progression of diabetic retinopathy (DR) on visual functioning (VF). DESIGN:Population-based cohort study. PARTICIPANTS:A total of 518 participants aged 40 to 80 years (baseline visit 2007-2009 and second visit 6 years later, 2013-2015), with diabetes...

journal_title：Ophthalmology

authors： Gupta P,Liang Gan AT,Kidd Man RE,Fenwick EK,Kumari N,Tan G,Mitchell P,Sabanayagam C,Wong TY,Cheng CY,Lamoureux EL

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Posterior vitreous detachment (PVD) plays an important role in vitreoretinal interface disorders. Historically, observations of PVD using OCT have been limited to the macular region. The purpose of this study is to image the wide-angle vitreoretinal interface after PVD in normal subjects using montaged OCT imag...

journal_title：Ophthalmology

authors： Tsukahara M,Mori K,Gehlbach PL,Mori K

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To delineate longitudinal changes in the optic nerve head (ONH) and peripapillary structure during myopia progression in childhood using spectral-domain (SD) OCT and to explore the factors associated with myopic ONH and peripapillary changes. DESIGN:Prospective cohort study. PARTICIPANTS:Twenty-three healthy ...

journal_title：Ophthalmology

authors： Kim M,Choung HK,Lee KM,Oh S,Kim SH

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To describe risk factors for scar formation and changes to fibrotic scar through 5 years in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN:Multicenter, prospective cohort study. PARTICIPANTS:A total of 1061 subjects in CATT. METHODS:Color photographic and fluorescein angi...

journal_title：Ophthalmology

authors： Daniel E,Pan W,Ying GS,Kim BJ,Grunwald JE,Ferris FL 3rd,Jaffe GJ,Toth CA,Martin DF,Fine SL,Maguire MG,Comparison of Age-related Macular Degeneration Treatments Trials.

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To present ophthalmic patient time-tradeoff vision utilities for quantifying vision-related quality-of-life when the fellow eye still has good vision. These utilities are important for performing reliable cost-utility analyses. DESIGN:Consecutive time-tradeoff vision utilities were obtained from ophthalmic pat...

journal_title：Ophthalmology

authors： Brown GC,Brown MM,Stein JD,Smiddy WE,Ophthalmic Utility Research Study Group.

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To determine whether differences between eyes in axial length (AL) and corneal power (K) on optical biometry are predictive of refractive outcomes. DESIGN:Retrospective cohort study. PARTICIPANTS:A total of 729 patients (1458 eyes) who underwent bilateral phacoemulsification at TLC (Mississauga, Ontario, Cana...

journal_title：Ophthalmology

authors： Kansal V,Schlenker M,Ahmed IIK

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:Motor vehicle accidents (MVAs) are a pandemic associated with human suffering and a burden to national economies. Whiplash-associated disorders (WADs) after MVAs are associated commonly with disability claims, many of which are related to vision. Convergence insufficiency (CI) leads to visual disability associa...

journal_title：Ophthalmology

authors： Stiebel-Kalish H,Amitai A,Mimouni M,Bach M,Saban T,Cahn M,Gantz L

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To provide a set of surveillance guidelines for children at risk for development of retinoblastoma. DESIGN:Consensus panel. PARTICIPANTS:Expert panel of ophthalmic oncologists, pathologists, and geneticists. METHODS:A group of members of the American Association of Ophthalmic Oncologists and Pathologists (AA...

journal_title：Ophthalmology

authors： Skalet AH,Gombos DS,Gallie BL,Kim JW,Shields CL,Marr BP,Plon SE,Chévez-Barrios P

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To determine in vivo confocal microscopy diagnostic criteria to diagnose Acanthamoeba keratitis (AK) using polymerase chain reaction (PCR) as the reference diagnostic technique. DESIGN:Retrospective case-control study. Data were recorded prospectively and analyzed retrospectively. PARTICIPANTS:Fifty patients ...

journal_title：Ophthalmology

authors： De Craene S,Knoeri J,Georgeon C,Kestelyn P,Borderie VM

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To compare overall survival in high-risk patients with primary uveal melanoma who received adjuvant sunitinib with institutional controls. DESIGN:Retrospective cohort. PARTICIPANTS:Selection criteria were (1) monosomy 3 and 8q amplification by cytogenetic or DecisionDx-UM Class 2 and (2) monosomy 3 and large ...

journal_title：Ophthalmology

authors： Valsecchi ME,Orloff M,Sato R,Chervoneva I,Shields CL,Shields JA,Mastrangelo MJ,Sato T

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To investigate when retinal pigment epithelium (RPE) tears occur and their associated treatment patterns and long-term visual outcomes in patients with neovascular age-related macular degeneration (nAMD) during anti-vascular endothelial growth factor (VEGF) treatment. DESIGN:Case-control analysis from a prospe...

journal_title：Ophthalmology

authors： Invernizzi A,Nguyen V,Arnold J,Young S,Barthelmes D,Gillies MC

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To compare structural outcome at age 4 years of eyes treated with intravitreal injection of bevacizumab with fellow eyes treated with conventional laser photoablation in type 1 retinopathy of prematurity (ROP). DESIGN:Single, randomized, controlled trial. PARTICIPANTS:All inborn babies with type 1 zone 1 ROP ...

journal_title：Ophthalmology

authors： Lepore D,Quinn GE,Molle F,Orazi L,Baldascino A,Ji MH,Sammartino M,Sbaraglia F,Ricci D,Mercuri E

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To define the range and life cycles of cuticular drusen phenotypes using multimodal imaging and to review the histologic characteristics of cuticular drusen. DESIGN:Retrospective, observational cohort study and experimental laboratory study. PARTICIPANTS:Two hundred forty eyes of 120 clinic patients with a cu...

journal_title：Ophthalmology

authors： Balaratnasingam C,Cherepanoff S,Dolz-Marco R,Killingsworth M,Chen FK,Mendis R,Mrejen S,Too LK,Gal-Or O,Curcio CA,Freund KB,Yannuzzi LA

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To evaluate the costs and cost-utility of examination for posterior vitreous detachment (PVD) and treatment of associated pathology, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD). DESIGN:A decision analysis model of cost-utility. PARTICIPANTS:There were no parti...

journal_title：Ophthalmology

authors： Yannuzzi NA,Chang JS,Brown GC,Smiddy WE

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To compare the efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation with mitomycin C (MMC) versus trabeculectomy with MMC. DESIGN:International, multicenter, retrospective interventional cohort study. PARTICIPANTS:Three hundred fifty-four eyes of 293 patients...

journal_title：Ophthalmology

authors： Schlenker MB,Gulamhusein H,Conrad-Hengerer I,Somers A,Lenzhofer M,Stalmans I,Reitsamer H,Hengerer FH,Ahmed IIK

更新日期：2017-11-01 00:00:00

abstract：:Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined disease. Patients with NCP are extremely challenging to manage, and evidence-based clinical recommendations for the management of patients...

journal_title：Ophthalmology

authors： Dieckmann G,Goyal S,Hamrah P

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:Assess the impact of false-positives (FP), false-negatives (FN), fixation losses (FL), and test duration (TD) on visual field (VF) reliability at different stages of glaucoma severity. DESIGN:Retrospective. PARTICIPANTS:A total of 10 262 VFs from 1538 eyes of 909 subjects with suspect or manifest glaucoma and...

journal_title：Ophthalmology

authors： Yohannan J,Wang J,Brown J,Chauhan BC,Boland MV,Friedman DS,Ramulu PY

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To compare the impact of first eye versus second eye cataract surgery on visual function and quality of life. DESIGN:Cohort study. PARTICIPANTS:A total of 328 patients undergoing separate first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the United States. Patien...

journal_title：Ophthalmology

authors： Shekhawat NS,Stock MV,Baze EF,Daly MK,Vollman DE,Lawrence MG,Chomsky AS

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To determine the personalized rate of uveal melanoma-related metastasis on the basis of individual tumor cytogenetic profile. DESIGN:Retrospective case series. PARTICIPANTS:A total of 1059 patients with uveal melanoma. METHODS:Fine-needle aspiration biopsy (FNAB) for DNA amplification and whole genome array-...

journal_title：Ophthalmology

authors： Shields CL,Say EAT,Hasanreisoglu M,Saktanasate J,Lawson BM,Landy JE,Badami AU,Sivalingam MD,Hauschild AJ,House RJ,Daitch ZE,Mashayekhi A,Shields JA,Ganguly A

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To determine whether the type of health insurance a patient possesses and a patient's race/ethnicity affect receipt of common tests to monitor open-angle glaucoma (OAG). DESIGN:Retrospective longitudinal cohort study. PARTICIPANTS:A total of 21 766 persons aged ≥40 years with newly diagnosed OAG between 2007 ...

journal_title：Ophthalmology

authors： Elam AR,Andrews C,Musch DC,Lee PP,Stein JD

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To document outer retinal tubulation (ORT) formation in advanced retinal disorders. DESIGN:Retrospective, observational study. PARTICIPANTS:Consecutive cases with retinal diseases showing outer retinal disruption and atrophy of the retinal pigment epithelium (RPE) associated with ORT on spectral-domain (SD) o...

journal_title：Ophthalmology

authors： Dolz-Marco R,Litts KM,Tan ACS,Freund KB,Curcio CA

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:We investigate whether responses on a Low Luminance Questionnaire (LLQ) in patients with a range of age-related macular degeneration (AMD) severity are associated with their performance on focal dark adaptation (DA) testing and with choroidal thickness. DESIGN:Cross-sectional, single-center, observational stud...

journal_title：Ophthalmology

authors： Yazdanie M,Alvarez J,Agrón E,Wong WT,Wiley HE,Ferris FL 3rd,Chew EY,Cukras C

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To use optical coherence tomography (OCT) to evaluate the femtosecond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism. DESIGN:Retrospective case series. PARTICIPANTS:Seventy-seven eyes of 77 patients. METHODS:Paired intrastromal incisions were created using the Catalys...

journal_title：Ophthalmology

authors： Wang L,Jiang L,Hallahan K,Al-Mohtaseb ZN,Koch DD

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To determine the prevalence of and factors associated with diabetic retinopathy (DR) among non-Indigenous and Indigenous Australian adults with self-reported diabetes. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Non-Indigenous Australians (50-98 years of age) and Indigenous Australians (40-92 ...

journal_title：Ophthalmology

authors： Keel S,Xie J,Foreman J,van Wijngaarden P,Taylor HR,Dirani M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To characterize treatment patterns and outcomes in eyes with treatment-naïve myopic choroidal neovascularization (mCNV) in the United States. DESIGN:Retrospective cohort study. PARTICIPANTS:Individuals aged 18 years and older seen in clinics participating in the American Academy of Ophthalmology's IRIS (Intel...

journal_title：Ophthalmology

authors： Willis J,Morse L,Vitale S,Parke DW 2nd,Rich WL,Lum F,Cantrell RA

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To evaluate the effect of glaucoma on functional vision and on vision-related (VR) and health-related (HR) quality of life (QoL) in children up to 16 years of age. DESIGN:Cross-sectional observational study. PARTICIPANTS:One hundred nineteen children 2 to 16 years of age (mean age, 9.4 years; standard deviati...

journal_title：Ophthalmology

authors： Dahlmann-Noor A,Tailor V,Bunce C,Abou-Rayyah Y,Adams G,Brookes J,Khaw PT,Papadopoulos M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To determine the microstructure of the fovea in patients with Stickler syndrome using imaging by spectral-domain optical coherence tomography (SD OCT) and swept-source OCT. DESIGN:Retrospective case series study. PARTICIPANTS:A total of 39 eyes of 25 patients with genetically confirmed Stickler syndrome were ...

journal_title：Ophthalmology

authors： Matsushita I,Nagata T,Hayashi T,Kimoto K,Kubota T,Ohji M,Kusaka S,Kondo H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To report the longitudinal change in axial length (AL) from the time of unilateral cataract surgery at age 1 to 7 months to age 5 years, and to compare AL growth of operated eyes with that of fellow unoperated eyes. DESIGN:Comparative case series. PARTICIPANTS:Infants enrolled in the Infant Aphakia Treatment ...

journal_title：Ophthalmology

authors： Wilson ME,Trivedi RH,Weakley DR Jr,Cotsonis GA,Lambert SR,Infant Aphakia Treatment Study Group.

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To study the adherence of rheumatologists to the hydroxychloroquine (HCQ) dosing guidelines established by the American Academy of Ophthalmology in 2011 and 2016. DESIGN:Retrospective review of electronic medical records (EMRs) in an integrated health care system. PARTICIPANTS:All rheumatology patients starte...

journal_title：Ophthalmology

authors： Braslow RA,Shiloach M,Macsai MS

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To expand understanding of presentation, diagnosis, and outcomes of hemorrhagic occlusive retinal vasculitis (HORV). DESIGN:Retrospective case series. PARTICIPANTS:Thirty-six eyes of 23 patients. METHODS:The American Society of Cataract and Refractive Surgery (ASCRS) and the American Society of Retina Specia...

journal_title：Ophthalmology

authors： Witkin AJ,Chang DF,Jumper JM,Charles S,Eliott D,Hoffman RS,Mamalis N,Miller KM,Wykoff CC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To determine the risks for altered cytogenetic profile based on melanoma features and size. DESIGN:Retrospective case series. PARTICIPANTS:A total of 1059 patients with uveal melanoma. METHODS:Fine-needle aspiration biopsy (FNAB) of tumor for DNA amplification and whole genome array-based assay. MAIN OUTCOM...

journal_title：Ophthalmology

authors： Shields CL,Say EAT,Hasanreisoglu M,Saktanasate J,Lawson BM,Landy JE,Badami AU,Sivalingam MD,Mashayekhi A,Shields JA,Ganguly A

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To compare rates of peripheral retinal changes in Age-Related Eye Disease Study 2 (AREDS2) participants with at least intermediate age-related macular degeneration (AMD) with control subjects without intermediate age-related changes (large drusen). DESIGN:Cross-sectional evaluation of clinic-based patients enr...

journal_title：Ophthalmology

authors： Writing Committee for the OPTOS PEripheral RetinA (OPERA) study (Ancillary Study of Age-Related Eye Disease Study 2).,Domalpally A,Clemons TE,Danis RP,Sadda SR,Cukras CA,Toth CA,Friberg TR,Chew EY

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:Diabetic patients have a greater risk of nonarteritic anterior ischemic optic neuropathy (NAION) than nondiabetic patients. We compare visual outcomes, prevalence of bilateral/sequential ION, and predictors of visual outcomes in NAION between diabetic and nondiabetic patients. DESIGN:Case-control study. PARTI...

journal_title：Ophthalmology

authors： Sharma S,Kwan S,Fallano KA,Wang J,Miller NR,Subramanian PS

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:The ability to detect reticular pseudodrusen (RPD)/subretinal drusenoid deposits (SDDs) using 12×12-mm widefield en face swept-source optical coherence tomography (SS-OCT) imaging was compared with conventional multimodal imaging (color, fundus autofluorescence (FAF), and infrared reflectance [IR] imaging) in e...

journal_title：Ophthalmology

authors： Schaal KB,Legarreta AD,Feuer WJ,Gregori G,Cheng Q,Legarreta JE,Durbin MK,Stetson PF,Kubach S,Rosenfeld PJ

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To compare monthly dosing with a treat and extend algorithm using ranibizumab 0.3 mg with and without angiography-guided macular laser photocoagulation for center-involving diabetic macular edema (DME). DESIGN:Multicenter, prospective, randomized clinical trial. PARTICIPANTS:A total of 150 eyes from 116 subje...

journal_title：Ophthalmology

authors： Payne JF,Wykoff CC,Clark WL,Bruce BB,Boyer DS,Brown DM,TREX-DME Study Group.

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To compare 2.0 mg ranibizumab (RBZ) injections with 0.5 mg RBZ for eyes with center-involved diabetic macular edema (DME). DESIGN:Randomized, controlled, double-masked (to the dose), interventional, multicenter clinical trial. PARTICIPANTS:A total of 152 patients (152 eyes) with DME. METHODS:Eligible eyes we...

journal_title：Ophthalmology

authors： Sepah YJ,Sadiq MA,Boyer D,Callanan D,Gallemore R,Bennett M,Marcus D,Halperin L,Hassan M,Campochiaro PA,Nguyen QD,Do DV,READ-3 Study Group.

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To investigate differences in clinical characteristics and genotype distribution in Japanese patients with age-related macular degeneration (AMD) and pseudodrusen using multimodal imaging. DESIGN:Retrospective, observational case series. PARTICIPANTS:A total of 101 patients (101 eyes) with AMD and pseudodruse...

journal_title：Ophthalmology

authors： Elfandi S,Ooto S,Ueda-Arakawa N,Takahashi A,Yoshikawa M,Nakanishi H,Tamura H,Oishi A,Yamashiro K,Yoshimura N

更新日期：2016-10-01 00:00:00

abstract：:This article describes the history of visual prostheses, with emphasis on the development of the Argus II retinal prosthesis system (Second Sight Medical Products, Inc., Sylmar, CA). A brief overview of cortical electrical stimulation in the blind is provided, followed by an account of the design and development of re...

journal_title：Ophthalmology

authors： Humayun MS,de Juan E Jr,Dagnelie G

更新日期：2016-10-01 00:00:00

abstract：:This article discusses the experience of progressing from a young ophthalmic resident to a full-time professional and, ultimately, to service on the American Board of Ophthalmology. ...

journal_title：Ophthalmology

authors： Alward WL

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:The human orbit is an environment that is vulnerable to inflammation and edema in the setting of autoimmune thyroid disease. Our study investigated the tenet that orbital adipose tissue lacks lymphatic vessels and analyzed the clinicopathologic differences between patients with acute and chronic thyroid eye dis...

journal_title：Ophthalmology

authors： Wong LL,Lee NG,Amarnani D,Choi CJ,Bielenberg DR,Freitag SK,D'Amore PA,Kim LA

更新日期：2016-09-01 00:00:00